Amaya Toman Spark
Spark is a desktop email client that aims to improve your relationship with email. Supports Gmail, Outlook, Microsoft 365, iCloud, Yahoo! Mail, Exchange and IMAP. Spark is packed with features that aim to make working with email more enjoyable and less overwhelming. Almost every app these days has a snooze and snooze feature, so Spark goes even further. The Command Center (accessed by pressing Command + K) allows you to quickly navigate your email accounts and learn keyboard shortcuts.
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canary mail
Canary Mail has always been a great email client. In terms of security, Canary supports end-to-end encryption with PGP, as well as its own SecureSend feature, which allows you to send encrypted messages to anyone regardless of what email service they use. For PGP, you can choose to use Canary's own PGP-based encryption (requiring the recipient to also use Canary), or advanced users can create their own PGP private keys. In contrast, SecureSend is as simple as flipping a switch when composing a new email—if the recipient doesn't have Canary, they'll need to log in to a secure website to see the message. Whichever way you have encryption turned on, no one but the intended recipient can read your message—not even your email provider.
Mailspring
Mailspring is an open-source alternative to native Mail. It is a fast and functional email client that allows you to easily set up multiple accounts. There is support for Gmail, Office 365, Yahoo! Mail, iCloud, Fastmail and more - Mailspring supports almost all email services. It offers advanced search, rich customization options and, last but not least, plugin support.
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mimestream
Mimestream is the best way to use Gmail on Mac. Unlike most Gmail apps for Mac, it's not just a web wrapper with keyboard shortcuts and notifications — it's a full-fledged macOS app that uses the Gmail API to keep all your Gmail accounts in one place.
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